Close Menu
  • News
  • Medical
  • Technology
  • Nanomaterials
  • Research
  • Blog
    • Nasiol.com
  • Contact
    • Tech7685@gmail.com
What's Hot

Nanoscale biosensor lets scientists monitor molecules in real time

May 30, 2025

How should we govern nanotechnology?

May 29, 2025

The Future of Needle-Free Immunization

May 28, 2025
Facebook X (Twitter) Instagram
Nanotech – Nanomaterials | Medical | Research | News Stories Updated Daily Nanotech – Nanomaterials | Medical | Research | News Stories Updated Daily
  • News
  • Medical
  • Technology
  • Nanomaterials
  • Research
  • Blog
    • Nasiol.com
  • Contact
    • Tech7685@gmail.com
Facebook X (Twitter) Instagram
Nanotech – Nanomaterials | Medical | Research | News Stories Updated Daily Nanotech – Nanomaterials | Medical | Research | News Stories Updated Daily
Home»Research»Advancing Pancreatic Cancer Treatment with Nanoparticle-Based Chemotherapy
Research

Advancing Pancreatic Cancer Treatment with Nanoparticle-Based Chemotherapy

November 21, 2023No Comments3 Mins Read
Facebook Twitter Pinterest Telegram LinkedIn Tumblr WhatsApp Email
Advancing Pancreatic Cancer Treatment with Nanoparticle-Based Chemotherapy
Share
Facebook Twitter LinkedIn Pinterest Telegram Email

Pancreatic cancer, a particularly lethal form of cancer and the fourth leading cause of cancer-related deaths in the western world, often remains undiagnosed until its advanced stages due to a lack of early symptoms.

Current treatments, like chemotherapies, have significant limitations, notably damaging healthy cells alongside tumor cells. However, recent advancements spearheaded by a collaboration between the Max Planck Institute for Multidisciplinary Sciences, University Medical Center Göttingen, and Karlsruhe Institute of Technology, focusing on the use of innovative nanoparticles.

Nanoparticle-Based Delivery of Chemotherapy

This novel approach utilizes nanoparticles for the precise delivery of the chemotherapy drug Gemcitabine directly to pancreatic tumor cells. Highlighting the potential of this method, Myrto Ischyropoulou, the lead author of the study, states: “Targeting the drug in high concentrations into the tumor cells with the help of the nanoparticles increases the efficacy and spares healthy cells. This can reduce the severe side effects that occur with Gemcitabine.” This targeted delivery system signifies a major advancement from the broader impact of conventional chemotherapy, which often adversely affects the patient’s overall health.

In preclinical trials, the nanoparticles have shown promise in transporting high quantities of Gemcitabine directly into the tumor cells of pancreatic cancer. The effectiveness of this method was confirmed using imaging techniques in mouse models, demonstrating that the nanoparticles specifically accumulate within the tumors. This targeted approach not only boosts the drug’s effectiveness against the tumor but also minimizes its harmful effects on healthy tissues.

Another advantage of this method is its potential to overcome the resistance mechanisms that tumors often develop against chemotherapy drugs. Claus Feldmann from KIT points out that free Gemcitabine is often ineffective due to the tumor’s resistance to drug uptake, but the nanoparticles introduce a different uptake mechanism in tumor cells, promising a more effective therapeutic approach.

See also  How nano’s gains are revolutionising the sports industry

The success of this research, illustrating the power of interdisciplinary collaboration, paves the way for further advances in the treatment of pancreatic cancer. The team is now working on optimizing this therapy for clinical application and transitioning the nanoparticles from the experimental phase to clinical use, facilitated by a spin-off company. This progression towards practical application not only signifies a leap in medical innovation but also mirrors the broader trends in the healthcare sector, particularly in oncology.

In the context of these developments, the pancreatic cancer treatment market is experiencing significant growth. According to Data Bridge Market Research, the market, which was valued at USD 2,236.17 million in 2021, is projected to expand to USD 6,245.81 million by 2029. This growth represents a Compound Annual Growth Rate (CAGR) of 13.70% during the forecast period from 2022 to 2029. Such growth is indicative of the increasing demand for more effective and targeted cancer treatments.

Conclusion

The development of nanoparticle-based chemotherapy for pancreatic cancer marks a pivotal shift towards more targeted and efficient cancer treatments. This breakthrough, poised to significantly reduce side effects and improve drug efficacy, aligns with the rapid growth and evolving dynamics of the cancer treatment market. As this technology progresses towards clinical application, it holds the promise of transforming the landscape of cancer therapy, offering new hope to patients battling one of the most challenging forms of cancer.

COMPANIES TO WATCH:

Merrimack Pharma, MagForce Nanotechnologies AG,

Author:

Kate Sivess-Symes

Content Producer and Writer

Nano Magazine | The Breakthrough 

Image

Source link

Advancing cancer Chemotherapy nanoparticlebased Pancreatic Treatment
Share. Facebook Twitter Pinterest LinkedIn Tumblr Email

Related Posts

Drug-loaded nanoparticles can enhance precision and safety of ultrasound tumor treatment

May 27, 2025

Biosensor uses pH-responsive DNA nanoswitches for highly sensitive bladder cancer detection in urine

May 24, 2025

Nanoparticle treatment combined with radiation therapy significantly improves glioblastoma survival in mice

May 3, 2025

In What Ways Can Nanosensors Be Used to Detect Cancer?

April 22, 2025

Ultra-thin, flexible silicone nanosensor could have huge impact on brain injury treatment

April 22, 2025

AI combined with nanotech can detect oral cancer earlier

April 21, 2025

Comments are closed.

Top Articles
Medical

Automated implant offers new hope for preventing opioid overdose deaths

Medical

Wake Forest Institute for Regenerative Medicine joins new NSF-funded pandemic prediction initiative

Research

The Roadmap to Integrating Sensing Capabilities into Daily Life

Editors Picks

Nanoscale biosensor lets scientists monitor molecules in real time

May 30, 2025

How should we govern nanotechnology?

May 29, 2025

The Future of Needle-Free Immunization

May 28, 2025

Nanoparticle-cell interface enables electromagnetic wireless programming of mammalian transgene expression

May 28, 2025
About Us
About Us

Your go-to source for the latest nanotechnology breakthroughs. Explore innovations, applications, and implications shaping the future at the molecular level. Stay informed, embrace the nano-revolution.

We're accepting new partnerships right now.

Facebook X (Twitter) Instagram Pinterest
Our Picks

Detecting lung cancer early with sugar-sensing nanotech

July 7, 2024

Ancient Architecture Technique Inspires Nanoscale Window to the Future

October 5, 2023

New “Better Than Graphene” Material Could Transform Implantable Technology

May 29, 2024

Subscribe to Updates

Get the latest creative Nano Tech news from Elnano.com

© 2025 Elnano.com - All rights reserved.
  • Contact
  • Privacy Policy
  • Terms & Conditions

Type above and press Enter to search. Press Esc to cancel.

Cleantalk Pixel