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Home » Explore PI’s Precision Motion Innovations for Life Sciences at Neuroscience 2025
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Explore PI’s Precision Motion Innovations for Life Sciences at Neuroscience 2025

October 29, 2025No Comments2 Mins Read
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This November in San Diego, top researchers and microscopy specialists will meet to exchange insights on the latest tools advancing life sciences. PI (Physik Instrumente) engineers will present high-precision motion and nanopositioning systems designed to enhance performance in super-resolution microscopy, live-cell imaging, and 3D optical metrology applications.

Advanced micro- and nanopositioning solutions for SR-microscopy, microtomy, DNA sequencing, cell manipulation, microsurgery, and patch clamp. Image Credit: PI (Physik Instrumente) LP

Direct-Drive Linear Stages for Microtomy

US-manufactured compact, precision linear stages, such as the V-141 and V-131 series, along with piezo nanopositioning stages, are well suited for microtome applications.

Piezo-Driven Nano-Focus Motors

PI’s P-725 piezo-driven nano-focus stage delivers 800 µm of vertical travel with sub-nanometer resolution, and msec response times – ideal for Z-stack image acquisition, OCT scanning, and two-photon microscopy. Its frictionless, wear-free flexure guides provide excellent precision and virtually unlimited lifetime. The fast focus motors come with an upgraded digital controller and software, compatible with major image acquisition platforms.

6-Axis Hexapod Manipulators for Microsurgery

PI’s high-precision hexapods enable coordinated motion in all six degrees of freedom with sub-micrometer repeatability, supporting microsurgery robotics, cobot and multi-axis microscopy tasks.

Low-Profile, High-Speed XY Stages

Using patented ultrasonic piezomotors, PI’s low-profile XY stages combine wide velocity ranges and excellent position stability, complete with a controller, joystick, and software for turnkey operation.

Microscopy and Bio-Nanotechnology Solutions

PI offers a full range of fast Z-sample stages and XYZ nanopositioning systems, enabling subatomic resolution, single-molecule microscopy, rapid 3D imaging, deconvolution microscopy, and fast auto-focusing to support life science research and bio-nanotechnology applications.

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Compact Voice-Coil Nanopositioning Stages for DNA Sequencing

PI’s latest voice-coil scanning stage provides 7 mm travel with nanometer resolution and user-adjustable magnetic preload for vertical operation of various microscope objectives. Its compact dimensions, high speed and high accuracy along with Ethercat-based drives make it ideal for OEM integration into multi-axis motion systems.

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PI (Physik Instrumente) LP

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